Clinical manifestations can change with age of the patient2
Please click on the age range below (age in years) to see when the clinical manifestations of cystic fibrosis begin.
Morbidity and mortality
Morbidity and mortality are mainly caused by bronchiectasis, small airways obstruction, and progressive respiratory impairment. Important comorbidities caused by epithelial cell dysfunction occur in the pancreas (malabsorption), liver (biliary cirrhosis), sweat glands (heat shock), and vas deferens (infertility)2